دکتر اصغرداوود-گروه شیمی دارویی

تعداد بازدید:۱۱۰

                              

                                                                                Curriculum Vitae

 Personal Details:

 First Name: Asghar

 Last Name: Davood                                                 

 Date of Birth: 1970/3/6 (1348/12/15)

 Place of Birth: Tehran

 Gender: Male

 Nationality: Iranian

 Marital Status: Maride

 Mailing address: 31, 4th Bahar Alley, Riazi bakhshayesh st., Sarv-e gharbi Ave., Sa’adat abad, Tehran, Iran

 Tel.: + 98 21 22131696 , 09120883948

 Fax: + 98 21 55619038, + 98 21 22640051-5.

 E-mail: adavood2001@yahoo.com, , adavood@iaups.ac.ir

Education:

1- Undergraduate  Studies:

 Pharm.D. from School of Pharmacy, Kerman University of Medical Sciences, Kerman,   

IRAN.

The title of Pharm.D. thesis: “Design, Synthesis and Antimicrobial evaluation of new                  derivatives of flouroquinolones”

Supervisor: Dr. Ali Reza Foroumadi

 

 2- Postgraduate  Studies:

 Ph.D.  in  Medicinal Chemistry, from School of Pharmacy, Isfahan University of Medical Science, Isfahan, IRAN.

The title of Ph.D. Thesis: "Design , Synthesis and pharmacological evaluation of new derivatives of 1, 4- dihydropyridines as Calcium Channel Modulators. ",

Supervisor: Dr. Abbas Shafiee

3- Postdoctoral fellowship Studies:

Postdoctoral fellowship in Medicinal Chemistry from school of pharmacy , University of Alberta, Edmonton, Canada.

The title of project: Design and Synthesis of a novel class of 

β-phenylethylidinehydrazine compounds for evaluation as agents to inhibit the enzymes monoamine oxiase ( MAO) and γ-aminobutyric acid transaminase (GABA-T).

Supervisor: Dr. E.E.Knaus

4- Visiting researcher:

     Research in organic chemistry and catalysis from the Faculty  of  Sciences, Organic Chemistry  

     and Catalysis, Utrecht University,Utrecht, Netherland.

      Title of project: Design and synthesis of new ligand as a iron chelator and catalysts.

     Supervisor: Dr. Robertus J. M. Klein Gebbink.

Academic  Positions:

  1. 2002  to  date    Lecturer in Medicinal chemistry, at Islamic Azad university, school of  

                                pharmacy.

  1. 2007  to date      Lecturer in inustrumental analysis (Spectroscopy and Chromatography), 

                          at Islamic Azad university, school of pharmacy.

  1. 2002  to date     Lecturer in general chemistry lab., at Islamic Azad university, school of 

                                pharmacy.

  1. 2002  to date     Supervisor in  65 undergraduate theses.

  1. 2005 - 2008       Lecturer in organic chemistry,   at Islamic Azad university, school of

                           Microbiology.

  1. 2005- 2007         Lecturer in organic chemistry lab.,   at Islamic Azad university, school of          

                           Medicine and biology.

  1. 2009-2011          Lecture in advanced organic chemistry.

  1. 1996-2002          Membership in Committee of Iranian Herbal Pharmacopoeia.

  1.  1996-2001        Assistant lecturer in Organic Chemistry, at Isfahan School of Pharmacy.

  1.  1996-2001        Assistant lecturer in Physicochemical Control of Drugs, at Isfahan School     

                                      of pharmacy.

  1. 1996-2001        Assistant supervisor in undergraduate theses, at Isfahan School of   

                         Pharmacy.

    Honors  and  Awards:

  1. The 3rd Medical Sciences Fewstival of Islamic Azad University (Loqman-e- Hakim),  prize for the top professor and lecturer in medical sciences and citation awarded by dean of Islamic Azad University (2016).

  1. Tehran Islamic Azad University, Pharmaceutical Sciences Branch,  prize for the top professor in pharmaceutical sciences branch and citation awarded by dean of pharmaceutical sciennces branch (2016).

  1. Tehran Islamic Azad University, Pharmaceutical Sciences Branch,  prize for the top researcher in pharmaceutical sciences branch and citation awarded by dean of pharmaceutical sciennces branch (2016).

  1. Tehran Islamic Azad University, Pharmaceutical Sciences Branch, prize for the  

                      cultural activity (Holly Quran) in pharmaceutical sciences branch and  citation 

                      awarded bydean of pharmaceutical sciennces branch (2016).

  1. Tehran Islamic Azad University, Pharmaceutical Sciennces Branch,  prize for the 

                       cultural activity (prayer) in pharmaceutical sciennces branch and  citation awarded      

                       by dean of pharmaceutical sciennces branch (2015).

   

  1. Tehran Islamic Azad University, Pharmaceutical Sciennces Branch, prize for the cultural elected in pharmaceutical sciennces branch and  citation awarded by dean of pharmaceutical sciennces branch (2014).

  1. Tehran Islamic Azad University, Pharmaceutical Sciennces Branch,  prize for the bestresearcher in pharmaceutical sciennces branch and  Holder of Gold  Coin and citation awarded by dean of pharmaceutical sciennces branch (2008).

  1. Tabriz  university of Medical Sciences prize for a paper in bioanformatic (2007).

  1. Isfahan  University of Medical Sciences prize for Top Ph.D. Student in Isfahan       

           University and Holder of Gold Coin and Citation Awarded by Dean of Isfahan     

           University of Medical Sciences(2004)

  1. Ministry of  Health & Medical  Education  Prize for  Top  Ph.D. Student in  National Board  and  Holder of Gold  Coin and Citation Awarded  by Minister of  Health(1998).

  1. Isfahan school of pharmacy prize for top Ph.D. student in national board  And top Ph.D. student in school of pharmacy and citation awarded by dean of school of pharmacy(1997).

 

  1. Kerman University of Medical Sciences prize for top undergraduate student in school of pharmacy and citation awarded by dean of Kerman University of Medical Sciences(1994).

  1. Kerman school of pharmacy prize for top undergraduate student in school of pharmacy and  citation awarded by dean of Kerman school of pharmacy(1993).

    

Experimental:

  1. Lecturer in Medicinal Chemistry, Organic Chemistry, Spectroscopy, Physicochemical Control of Drugs and general chemistry lab.

  1. Supervisor in undergraduate theses .

  1. Pharmacological (Calcium channel madulatoratory) and Antimicrobial evaluation.

  1. Synthesis of organic compounds and drugs.

  1. Operatory of  NMR, IR and FT-IR spectrophotometers.

  1. Polymer synthesis.

  1. Computer aided drug design:  QSAR, Docking, protein homology modeling.

  1. Ability to working with specific software such as  Gromacs, Modeller, Autodock tools, Gaussian,  CP, CW, Chemdraw, Nemesis ,Hyperchem, Chemdraw, Dragon, ChemSketch and Alchemy.

  1. Interpretation of IR, FT-IR, H1-NMR, C13-NMR, F19-NMR, UV, GC, HPLC, Mass spectra and elemental analysis.

  1. Isolation and purification of organic compounds, natural products and drugs by Column Chromatography, Flash Chromatography, Tin Layer Chromatography, Recrstalization, Distillation at atmospheric pressure, Fractional distillation at atmospheric pressure, Steam distilation, Distillation under diminshed pressure (vacuum distillation), Sublimation and Extraction.

  1. Ability to working with common softwares such as  SPSS, Matlab, Microsoft office,  Photoshop and Excell.

Patents:

Alen Shahbazian, asghar davood, alireza dabirsiaghi, production of industrial piroxicam   polymorphs and optimization of dissolution rate of powder. Iran patent, 89/ الف   015638,  1393/04/08 -  83201.

Papers:

  1. A. Foroumadi, S. Emami, A. Davood, M. Moshafi, A. Sharifian, M. Tabatabaie, H. Tarhimi, G. Sepehri, A. Shafiee; Synthesis and In-vitro antibacterial activities of N- substitued piperazinyl quinolones, Pharmaceutical Sciences 1997, 3: 559-563.
  2. A. Foroumadi, A. Davood, M. Mirzaei, S. Emami, M. Moshafie; Synthesis and antibacterial activity of some novel N- substituted piperazinyl quinolones, Boll. Chim. Farm. 2001, 140(6): 411-6.
  3. A. Davood, G. Khodarahmi, E. Alipour, A. Dehpour, A. Amini, A. Shafiee; Synthesis and calcium channel antagonist activity of nifedipine analogues containing 4(5)-chloro-2-methyl-5(4)-imidazolyl substituent; Boll. Chim. Farm. 2001, 140(6): 381-6.
  4. A. Foroumadi, F. Soltani, S. Emami, A. Davood; Antituberculosis agents. III. In-vitro evaluation of antimycobacterial activity and cytotoxicity of some N-piperazinyl quinolone derivatives; Boll. Chim. Farm. 2002, 141(3): 247-9.
  5. B. Sowa, G. Rauw, A. Davood, A. Fassihi, E. E. Knaus, G. B. Baker, Design and biological Evaluation of phenyl – substituted analogs of B-phenylethylidenehydrazine. Bioorg Med Chem. 2005, 13 : 4389-4395.
  6.  A. Davood, N. Mansouri, A. R. Dehpour, H. Shafaroudi, E. Alipour, A. Shafiee. Design,

         synthesis and calcium channel antagonist activity of new 1,4- dihydropyridines containing

         2-ethyl-4(5)- chloro- 5(4)- imidazolyl substituent in ginea - pig ileal smooth muscle.     

         Archiv Der pharmazie, 2006, 339(6): 299-304.

  1. A. Davood, E. Alipour, A. Shafiee,  Efficient synthesis of imidazole derivatives : An      

           important synthons for preparing  biologically active compounds, Turk. J. Chem., (2008), 

           32, 389-395.

  1.  Erin M. MacKenzie, Afshin Fassihi, Asghar Davood, Qiao-Hong Chen, Gillian Rauw, Gail Rauw,Edward E. Knaus, and Glen B. Baker, Design and Biological Evaluation of N-Propynyl Analogs of β-Phenylethylidenehydrazines, Bioorg.Med.Chem.2008, 16(17), 8254-8263.

  1. Asghar Davood, Maryam Iman, Masoumeh Majd, Drugs and G6PD deficiency; prophylaxy is better than treatment. 2008,233(7), 29-40, RAZI.
  2. Asghar Davood, Alireza nematollahi, Arash Nabbi, Design and modeling studies on   isoindole derivatives as a novel non-classical Anti bacterial agents, The Internet Journal of Medical Informatics, 2009,4,1.

  1.  Asghar Davood, Alireza nematollahi, Maryam Iman, Abbas Shafiee, Computational studies of new 1,4-Dihydropyridines containing 4-(5)-Chloro-2-ethyl-5-(4)-imidazolyl substituent: QSAR and Docking , Medicinal Chemistry Research, 2010,19(1),58-70.

  1.  Asghar Davood, Alireza nematollahi, Maryam Iman, Abbas Shafiee, Synthesis and docking  studies of new 1,4-Dihydropyridines containing 4-(5)-Chloro-2-ethyl-5-(4)-imidazolyl substituent as novel calcium channel agonist, Arch.Pharm.Res. 2009, 32(4), 481-487.

  1. M. Iman, A. Davood, A. nematollahi, A.R. Dehpour,  A. Shafiee, Design, synthesis and calcium channel antagonist activity of new    1,4- dihydropyridines containing 4(5)- chloro- 5(4)- imidazolyl substituent in ginea - pig ileal smooth muscle, Arch.Pharm.Res. 2011, 34(9), 1417-1426 .
  2. Asghar Davood, Maryam Iman, Alireza Nematollahi, A. Shafiee, Docking and QSAR studies of new 1,4-dihydropyridines containing 4(5)-chloro-2-methyl-5(4)-imidazolyl substituent. Med Chem Res (2012) 21:325–332.

  1. Asghar Davood , Maryam Iman,  Docking and QSAR studies of β-phenylethylidene hydrazine derivatives as a Gamma-aminobutyric acid aminotransferase inhibitor. Med. Chem. Res. 2011, 20, 955-961.

  1. M. A. Monavarasli, L. Firoozpour, V. Sheibani, D. N. Sarkandi, A. Sakhteman, A. Davood,  A. Shafiee, A. Foroumadi, Synthesis of 1-benzyl-4-[2-(thienylcarbonylamino) ethyl]piperidine as a novel potential cholinesterase inhibitor, Asian j. Chem. (2011), 23, No. 6 , 2487-2490

  1. D.N. Sarkandi, L. Firoozpour, V. Sheibani, M. A. Monavar, A. Davood, A. Shafiee, A.  

          Foroumadi, synthesis of 1-benzyl-4-[2-(5-phenyl-1,3,4-thiadiazole-2-yl)aminoethyl]   

          piperidine as potential alzheimer’s disease modifying agent, Asian j. Chem. (2011), 23, No.  

         6 , 2503-2505

  1.  A. Davood, H. Shafaroudi, M. Iman, Molecular modeling and protection against  

       pentylenetetrazole - induced seizure of new 1,4-dihydropyridinescontaining 5(4)-

       imidazolyl substituent, Medicinal Chemistry Research ( 2012), 21, No 11;3767-3776.

  1.  A. Davood,  , H. Shafaroudi, M. Amini, A. Nematollahi, A. Shirazi, M. Iman, L. Azimidost. Design, Synthesis and protection against pentylenetetrazole-induced Seizure of N-aryl derivatives of  the phthalimide pharmacophore, Medicinal Chemistry, 2012, 8, 953-963.

  1.  Asghar Davood, Maryam Iman, Molecular docking and QSAR study on   imidazole derivatives as 14α-demethylase inhibitors.  Turk.J.Chem. 2013, 37, 119-133.

  1.  S. Saeidnia, M.S. Nourbakhsh, A.R. Gohari, A. Davood, Isolation and Identification of the Main  Compounds of Satureja sahendica Bornm, Australian Journal of Basic and Applied 

           Sciences, 5(6):1450-1453, 2011

  1. Alireza Nematollahi, Asghar Davood, Docking and QSAR studies of novel (E)-3-(4-

           methanesulfonylphenyl)-2-(aryl) acrylic acids as dual inhibitors of cyclooxygenases and  

           lipoxygenases, Int.J. ChemTech Res.2010,2(3).

  1. Asghar Davood,  Mohsen Amini,  Leila Azimidoost, Somaieh Rahmatpour, Ali Nikbakht,  

           Maryam  Iman , Hamed Shafaroodi,   Abdollah Ansari, Docking , Synthesis  and    

           pharmacological evaluation of  isoindoline  derivatives as anticonvulsant agents.  

          Med.Chem.Res     2013; 22( 7), 3177-3184

  1. Maryam Iman, Asghar Davood, QSAR and QSTR study of pyrimidine derivatives to 

           improve their therapeutic index as antileishmanial agents. Med.Chem.Res. 2013, 22: 5029-

           5035.

  1. Asghar Davood, Atefeh Saadabadi, Maryam Iman, Docking studies of phthalimide 

           pharmacophore as a sodium channel blocker. Iran J Basic Med Sci   2013; 16: 1016-1021.

  1. Asghar Davood, Maryam Iman, Homology Modeling of Lanosterol 14α-Demethylase of 

          Candida albicans and Insights into azole binding, Med.Chem.Res  (2014) 23:2890–2899.

  1. Maryam Imana, Asghar Davood, QSAR and QSTR study of selenocyanate derivatives to

           improve their therapeutic index as antileishmanial agents.Med.Chem.Res. (2014) 23: 818-

           826.

  1. Soroush Sardari, Kayhan Azadmanesh, Fereidoun Mahboudi, Asghar Davood, Ruhollah  

           Vahabpour, Rezvan Zabihollahi, and Hosna Gomari;  Design of Small Molecules with   

           HIV Fusion Inhibitory Property Based on Gp41 Interaction Assay; Avicenna J Med

           Biotechnol. 2013 Apr-Jun; 5(2): 78–86.

  1. Maryam Iman, Asghar Davood, Nasim Banarouei, QSAR study of chalcone derivatives as

           anti-leishmania agents. Turk.J.Chem.,2014, 38, 716-724.

  1. Maryam Imana, Asghar Davood, Bert Klein Gebbink, Parisa Azerang, Mona Alibolandi,

           Soroush Sardari, Design and antimicrobial evaluation of 1-methylimidazole derivatives as 

           new antifungal and antibacterial agents. Pharmaceutical Chemistry Journal. 2014, 48,8,  

          1140-5.

  1. Asghar Davood, Liela Azimidoost,  Hamed Shafaroodi, Mohsen Amini, Abdollah Ansari, Ali Nikbakht,  Maryam Iman, Somaieh Rahmatpour, Ali reza Nematollahi, Docking and

          Synthesis of 2-arylisoindoline-1,3-dione derivatives as  anticonvulsant agents. 

          Pharmaceutical Chemistry Journal, 2014, 48, 3, 175-180.

  1. Asghar Davood, Maryam Iman, Yassamin ebrahimi nassimi, In silico studies on triazole 

 derivatives as antifungal agents , Journal of Health Policy and Sustainable Health  

 (JHPSH), 2014, 1(3), 57-63.

  1. Maryam Iman, Asghar Davood, Computational study of quinolone derivatives to improve 

their therapeutic index as anti-malaria agents: QSAR and QSTR, Iranian Journal of  Pharmaceutical Research (IJPR), (2015), 14 (3): 775-784.

  1. Maryam Iman, Atefeh Saadabadi , Asghar Davood, Molecular docking analysis and 

       molecular dynamics simulation study of ameltolide analogous as a sodium channel 

 blocker.Turk.J.Chem. (2015) 39: 306-316.

  1. Asghar Davood, Bahare Asna Ashari, Maryam Iman; Docking and QSAR studies of triazole derivatives as more potent and effective antifungal agents;  Journal of Military Medicine (J Mil Med), (2015),17(2):100-105.

  1. Rejali L, Moshtaghian SJ, Mahzouni P, Davood A. The effect of chronic consumption of silver nanoparticles on thyroid gland and pregnancy in rat. Qom Univ Med Sci J (2015);9(7):20-28.

  1. Asghar Davood, Golnoush Dehqani, Mahboubeh Lotfinia, Mohsen Amini, Soroush Sardari, Parisa Azerang, Maryam Iman, Design, Synthesis and evaluation of antitubercular activity of novel dihydropyridine containing imidazolyl substituent, Iranian Journal of Pharmaceutical Research (2015), 14(4), 1067-1075.

  1. Osvaldo Garrido-Acosta, Sergio E Meza-Toledo, Liliana Anguiano-Robledo, Marvin A Soriano-Ursúa, Jose Correa Basurto, Asghar Davood and Germán Chamorro Cevallos, Anticonvulsant and toxicological evaluation of para-fluorinated/chlorinated derivatives of 3-hidroxy, 3-ethyl, 3-phenylpropionamide, Biomed Res Int. 2016;2016:3978010. doi: 10.1155/2016/3978010. Epub 2016 Feb 24.

  1. Alen Shahbazian, asghar davood, alireza dabirsiaghi,Application of Taguchi method to 

  investigate the effects of process factors on the production of industrial piroxicam  

  polymorphs and optimization of dissolution rate of powder. Iran J Pharm Res. 2016 ;15(2):395-401.

  1. Asghar Davood,  Mahboubeh Lotfinia, Golnoush Dehqani,  Mohsen Amini, Soroush Sardari, Parisa Azerang, Maryam Iman, Design, synthesis and anti-tubercular activity of novel 1, 4- dihydropyrine-3, 5-dicarboxamide containing imidazole substituent, Iranian Journal of Pharmaceutical Research. (2016), 15(4), 791-799.

  1. Maryam Iman, Hamed Shafaroodi, Asghar Davood, Masoud Abedini. Pouyan Pishva, Taherkhani, Ahmad reza Dehpour, Abbas Shafiee, Design and synthesis of  2- (arylmethylideneamino) isoindolines as new potential analgesic and anti inflammatory agents: A molecular hybridization approach. Curr Pharm Des. (2016), 22(37), 5760-5766.

  1. Asghar Davood, Talin boghoos piromian, Mohsen Amini, Soroush Sardarid, Parisa Azerang; Design, synthesis and antimicrobial evaluation of new azoles:  A molecular hybridization approach; Pharmaceutical Chemistry Journal. (2016), 49(10), 687-693.

  1. Asghar Davood, Atefeh Saadabadi, Hamed Shafaroodi, Ali Nikbakht, Abdollah Ansari, 

Masood Abedini, Docking, Synthesis and anticonvulsant activity of N-substituted 

      isoindoline-1,3-dione. Iranian Journal of Pharmaceutical Research (2017), 16(2), 589-595.

  1. Asghar Davood, Aneseh Rahimi, Parisa Azerang, Soroush Sardari, Arash Mahboubi,

 Maryam Iman, Design and synthesis of new antifungals based on N- un-substituted 

Azoles, pharmaceutical chemistry journal (accepted).

  1. Asghar Davood, Hanieh Pouriaiee,  Hamed Shafaroodi, Maryam Iman,  Sepideh Akhbari, 

Leila Azimidoost, Erfan Imani, Somaieh Rahmatpour, New derivatives of phthalimide with potent anticonvulsant activity in PTZ  and MES seizure models. Iran J Basic Med Sci   (2017), 20(4), 430-437.

  1. Maryam Iman,  Zeynab Khansepid, Asghar Davood Modeling and proposed mechanism of Hydroxyurea through docking and molecular dynamic simulation to curtail the action of

           ribonucleotide reductase. Recent Pat Anticancer Drug Discov. (2016), 11(4), 461-468.

  1.  Iman M, Kaboutaraki HB, Jafari R, Hosseini SA, Moghimi A, Khamesipour A, Harchegani AB, Davood A, Molecular Dynamics simulation and docking studies of selenocyanate derivatives as anti-leishmanial agents. Comb Chem High Throughput Screen. 2016 , 19(10); 1-8.

  1. Asghar Davood, Yasaman Rasouli, Armin Alaee, Golnoush Dehqani, Hamed Shafaroudi, 

Mahboubeh Lotfini, Anticonvulsant effects of new 1, 4-dihydropyridine derivatives 

           containing imidazolyl moiety against seizures induced by Pentylenetetrazole and Maximal 

Electroshock in mice, Iranian Journal of Pharmaceutical Research (2017), 16(3), 893-903.

  

  1. Elahe Qudjani, Asghar Davood, Mahdi Fasihie, Maryam Iman, Synthesis of curcumin-like diarylpentanoid analogues as potential anticancer agents, Recent Pat Anticancer Drug Discov. 2016;11(3):342-51.

  1. Yasaman Rasouli, Asghar Davood, Hybrid docking-QSAR studies of non-hydrolyzed and hydrolyzed 1, 4-dihydropyridine-3, 5-dicarboxamides as potential antitubercular agents.

Current Computer-Aided Drug Design (2018), 14(1), 35-53.

  1. Zeynab Khansefid, Asghar Davood, Mahdi Fasihi, Maryam Iman, Synthesis, in-silico and in-vitro cytostatic activity evaluation of new lipophilic derivatives of hydroxyurea to improve pharmacokinetic profile, Recent Pat Anticancer Drug Discov.2018, 13(3):378-385 (2018)
  2. Nasimosadat Banaroiee, Asghar Davood, Maryam Iman, Hamed Shafaroodi, Abbas Shafiee; N-arylmethylideneaminophthalimide: Design, synthesis and evaluation as analgesic and anti-inflammatory agents, Mini-reviews in Med. Chem. 2019;19(8):679-687.

  1.  A. Saadabadi, B. Kohen, A. Davood, M. Irandost, M. Rezayat, 2, 5-Disubstituted phthalimides: design, synthesis and anticonvulsant activity in scPTZ and MES models. Current computer-aided drug design, 2018, 14, 310-321

  1. Maryam Iman; Sina Fakhari; Mohammad jahanpanah; Nima Naderi; Asghar Davood,  Design and Synthesis of 4-flurophthalimides as potential anticonvulsant agents. IJPR, (2018), 17(3): 896–905.

  1. Mehrnoush Molaeian, Asghar Davood, Mahmoud Mirzaei, Non-Covalent Interactions of N-(4-CarboxyPhenyl)Phthalimide with CNTs, Adv. J. Chem. B 2020;2(1):39–45.

  1. Maryam Iman, Asghar Davood, Ali Khamesipour, Design of antimalarial agents based on pyrimidine derivatives as methionine aminopeptidase 1b inhibitor: Molecular docking, quantitative structure activity relationships, and molecular dynamics simulation studies, J Chin Chem Soc.2020;1–11.

  1. Asghar Davood,Maryam Iman,  Mohammad Reza Taheri, Design and Docking Study of Some Pyrimidine derivatives as Antimalarial Agents, Journal of Military Medicine, 2020,22, 314-322.

  1. Asghar Davood, Aneseh Rahimi, Maryam Iman, Parisa Azerang, Soroush Sardari, Arash Mahboubi, Design and synthesis of new antifungals based on N- un-substituted azoles as 14α demethylase inhibitor, Curr Comput Aided Drug Des,2020, doi: 10.2174/1573409916666200217090855.

  1. Shahla Shokri, Hoda Ayazi, Mohsen Tamjid, Fatemeh Ghoreishi, Mahsa Shokri, Sogol Badakhshan Nouri, Nima Naderi, Bahram Daraee, Zahra Mousavi, Asghar Davood, Hybrid analogues of hydrazone and phthalimide as high therapeutic index analgesic: Design, synthesis, cyclooxygenase inhibitory and analgesic activity. J Chin Chem Soc. Chem (under review) .
  2. Vahid Askari, Maryam Iman, Homa Manahegi, Ahmad R.Dehpour, Nastaran Rahimi,  Asghar Davood, Evaluation of Analgesic Effect of Phthalimide Derivatives, Using the Hargreaves Test in Mice. Journal of Biological Physics (under review).

Presentation  (Orals and Poster):

 

  1. A. Foroumadi, A. Sharifian, S. Emami, A. Davood, Y. Tabatabiee, G. Sepehri, A. Shafiee; Synthesis and antimicrobial activity of N- (2-oxyimino-2-phenyl ethyl) quinolone derivaties; AFMC Int. Med. Chem. Symp. Tokyo, Japan, P6 (1995).

  1. A. Foroumadi, A. Sharifian, S. Emami, A. Davood, Y. Tabatabiee, G. Sepehri, A. Shafiee;  Synthesis and antimicrobial activity of N- (2-oxyimino-2-phenyl ethyl) quinolone Derivaties, 12th congress of Iranian physiology and pharmacology, Tehran, Iran, P226 ( 1996).

  1. A. Davood, J. Asili, H. Golafshan, N. Baghaiee; Synthesis and antimicrobial activity of

 N-(triflouromethansolphonyl) and N-(methansolphonyl)- Norfloxacin, 4th Congress of   

 Iranian Pharmaceutical Students, Shiraz, Iran, P22 (1997).

  1. A. Davood, A. Shafiee; Design and synthesis of new derivatives of 1,4-dihydropyridines, Meeting of Medicinal Chemistry, Isfahan, Iran, 1999.

  1. A. Davood, E.E. Knaus; Design and synthesis of Monoamine oxidase and Gaba-Aminobutyric Acid Transaminase Inhibitors, Meeting of Medicinal Chemistry, Isfahan, Iran, 2002.

  1. A. Davood, Methods of drug design, Congress of Pharmaceutical Sicences, Isfahan, Iran, 2003.

  1. A. Davood, E. Alipour, A. Shafiee, synthesis of new 1,4- dihydropyridines containing

            4(5)- chloro- 5(4)- imidazolyl substituent, 9th Iranian seminar of pharmaceutical sciences,     

            Tabriz, Iran, p , (2004)

  1. J. Najd, M. M. Habibi, A. Davood, QSAR of nifedipine analogues containing 4(5)-chloro- 

            2- ethyl-5(4)-imidazolyl substituen as a calcium channel antagonist , 10th Congress of 

            Iranian Pharmaceutical Students, Shiraz, Iran, P , (2005).

  1. Y. Septi, F. Kobarfard ,A. Davood, P. Farnia, , Preparing  new derivatives of isoniazid as  

 Potentially effective compounds of antitubercular. 12th Congress of Iranian Pharmaceutical Students, Sari, Iran, P84 (2006).

  1. N. Ahmadzadeh, F. Kobarfard, A. Davood, Synthesis of  new derivatives of         

            thiosemicarbazone derivatives as potential antituberculosis compounds, 12th Congress of 

            Iranian  Pharmaceutical Students, Sari, Iran, P89 (2006).

  1. S. Haj mohammad ebrahim ketabforoosh, F. Kobarfard, A. Davood, P. Farnia, Synthesis of semicarbazone derivatives as potential antituberculosis compounds, 12th Congress of   

            Iranian  Pharmaceutical Students, Sari, Iran, P102 (2006).

  1. Ehsan Tavasoli, Asghar Davood, Abbas Tabatabaiee, Application of computer in     

     Medicinal Chemistry, 12th Congress of Iranian  Pharmaceutical Students, Sari, Iran, P256  

      (2006).

  1. Y. Septi, A. Davood, P. Farnia, F. Kobarfard, Synthesis of new derivatives of isoniazid as   

            potential anti mycobacterium compounds, 10th Iranian seminar of pharmaceutical 

            sciences, Tehran, Iran, p , (2006)

  1. S. Haj mohammad ebrahim ketabforoosh, F. Kobarfard, A. Davood, P. Farnia, Synthesis of  new semicarbazone derivatives as potential antituberculosis compounds, 10th Iranian   

            seminar of pharmaceutical sciences, Tehran, Iran, p , (2006).

.

  1. N. Ahmadzadeh, F. Kobarfard, A. Davood, P. Farnia, Synthesis of  new thiosemicarbazone derivatives as potential antituberculosis compounds, 10th Iranian    seminar of  pharmaceutical sciences,  Tehran, Iran, p , (2006).

  1. A. Davood, Role of the natural products in finding of lead compounds, Meeting of natural

         products, Tehran, Iran, 2006.

  1. A. Davood, Developing Therapeutics for the Treatment of Multiple Sclerosis, Meeting of

    Pharmacy , Tehran, Iran, 2007.

  1. M. Lotfinia, M. Iman, A. Davood, M. Amini, Design, synthesis and antimicrobial activity  

            of new 1,4- dihydropyridines containing  4(5)- chloro-2-ethyl- 5(4)- imidazolyl 

            substituent, 13th Congress of Iranian Pharmaceutical Students, Tabriz, Iran, P78 , (2007).

  1. S. Khakpoor, A. Nematollahi, A. Davood,Design of 1,4-dihydropyridines for overcoming

            ABC-mediated transporter multidrug resistance ( MDR), 13th Congress of Iranian

            Pharmaceutical Students, Tabriz, Iran, P79 , (2007).

  1. S. Shamshaeari, A. Nematollahi, A. Davood, Evaluation of green chemistry as a esential   

            course  in pharmacy, 13th Congress of Iranian Pharmaceutical Students, Tabriz, Iran,

            P117(2007).

  1. Maryam Iman, Asghar Davood, Masoumeh Majd, Drugs and glucose-6-phosphate dehydrogenase (G6PD) deficiency.11th Iranian Pharmaceutical Sciences Conference, Kerman, Iran, P96 (2008).

  1. Ali Reza Nematollahi, Asghar Davood, Synthesis and docking studies of new 1,4-dihydropyridines containing 4(5)- chloro-2-ethyl-5(4)-imidazolyl substituent as novel calcium channel agonist, 11th Iranian Pharmaceutical Sciences Conference, Kerman, Iran, P167(2008).

  1. Asghar Davood, Maryam Iman, Erfan Imani, Ahmad Reza Dehpour, Docking, QSAR, Synthesis and calcium channel antagonist activity of new 1,4-dihydropyridines containing 4(5)-chloro-5(4)-imidazolyl substituent in Ginea pig ileal smooth muscle, 11th Iranian Pharmaceutical Sciences Conference, Kerman, Iran, P167-168 (2008).

  1. Asghar Davood, Maryam Iman, Sepide Akhbari, Computational studies of new 1,4-dihydropyridines containing 4(5)- chloro-2-ethyl-5(4)-imidazolyl substituent: QSAR and docking, 11th Iranian Pharmaceutical Sciences Conference, Kerman, Iran, P1170 (2008).

  1. F. Araghi, N. Bozorgi, A. Nematollahi, A. Davood, The computational studies on the mechanisms of isoindole derivatives as a novel antibacterial agents, 11th Iranian Pharmaceutical Sciences Conference, Kerman, Iran, P171 (2008).

  1. Ali Rezaei Mokarram, Asghar Davood, Maryam Iman, Effect of polymer molecular weight And its N-trimethyl derivatives on in-vitro properties chitosan nanoparticles as a new carrier In vaccine delivery, 2nd International congress on nanoscience and nanotechnology, Tabriz, Iran (2008).

  1. Mahdiye Sadat Noorbakhsh, Sepide Akhbari, Asghar Davood, The beneficial use of RFID     in pharmacy and hospitals, The 14th seminar of iranian pharmacy students, Ahvaz, Iran, 221 ( 2009).

  1.  Elaheh Safara, Asghar Davood, Arezoo Ahmadi, Alireza Nematollahi, Computational studies of new 1,4-Dihydropyridines containing 4-(5)-chloro-2-methyl-5-94)-imidazolyl substituent: QSAR and Docking, The 14th seminar of iranian pharmacy students, Ahvaz, Iran, 232-233( 2009).

  1.  Sara Atayi, Asghar Davood, Alireza Nematollahi, Fatemeh Sarafzadeh Javidi, Docking and QSAR studies of novel (E)-3-4-(4-methansulfoylphenyl)-2-(aryl)acrylic acids as dual inhibitors of cyclooxygenases and lipoxygenases,  The 14th seminar of iranian pharmacy students, Ahvaz, Iran, 234( 2009).

  1.  Asghar Davood, Maryam Iman, Favism and drugs  '11th Iranian Pharmaceutical Science Congress. Kerman-Iran (2008).

 

  1. Asghar Davood, Maryam Iman, Design and synthesis of new phthalimides as anticonvulsant agents. The 12th Iranian pharmaceutical Sciiences Congress (IPSC 2010), zanjan, Iran.

  1.  Asghar Davood, Design and synthesis of new  N-aryl isoindoles as a anticonvulsant agents , The 12th Iranian pharmaceutical Sciiences Congress (IPSC 2010), zanjan, Iran.

  1. Arezo Ahmadi, Asghar Davood, 15th Seminar of Iranian Pharmacy Students. (2010).

  1.  Arezo Ahmadi, Asghar Davood, Synthesis of new derivatives of aryl thiosemicarbazones 16th Iranian pharmacy Students Seminar, (2011), Tehran, Iran.

  1. Atefeh Saadabadi, Asghar Davood, Docking analysis of a series of (1H)isoindole-1, 3(2H)dione as new anticonvulsant agents. 16th Iranian pharmacy Students Seminar, (2011), Tehran, Iran.

  1. Taha, Taqizadeh,  Asghar Davood, Design and synthesis of new derivatives of pyrrolopyridine as anticonvulsant agents. 16th Iranian pharmacy Students Seminar, (2011). Tehran, Iran.

  1.  Soroor Oliyaei, Nader Saemian, Asghar Davood, Gholam Hossein Shirvani, Synthesis of 4-amino butyric acid (GABA) labelled with deuterium or tritium, 15th Seminar of Iranian Pharmacy Students. (2010).

  1. Haniyeh Pouriaie, Asghar Davood, Hamed Shafaroodi, The study of isoindole derivaties on PTZ and MES-induced clonic and tonic seizure in male mice.  The 13th Iranian pharmaceutical Sciiences Congress (IPSC 2012), Isfahan, Iran, 2012;7(5).

 

  1.  Atefeh Saadabadi, Asghar Davood, Design and synthesis of isoindole derivatives as new anticonvulsant agents  The 13th Iranian pharmaceutical Sciiences Congress (IPSC 2012),  Isfahan, Iran, 2012;7(5).
  2. Bahareh asnaashari, Asghar Davood, Synthesis and docking studies of novel antifungals based on 4-substituted imidazole  The 13th Iranian pharmaceutical Sciiences Congress (IPSC 2012), Isfahan, Iran, 2012;7(5).

  1. Yasaman ebrahimi, Asghar Davood, Bahare Asnaashari, Design and synthesis of 4-substituted azoles and prediction of their binding to 14α-demethylase using molecular docking. The 13th Iranian pharmaceutical Sciiences Congress (IPSC 2012), Isfahan, Iran, 2012;7(5). 

  1. Yasaman ebrahimi, Asghar Davood, Molecular docking of biaryloxy-substituted triazoles as lanosterol 14-demethylase inhibitor The 13th Iranian pharmaceutical Sciiences Congress (IPSC 2012), Isfahan, Iran, 2012;7(5).

  1. Nasimosadat Banarouyi, Asghar Davood, Design and synthesis of 2-(benzylideneamino)isoindolines, The 13th Iranian pharmaceutical Sciiences Congress (IPSC 2012), Isfahan, Iran, 2012;7(5).

  1. Nazanin qanbari, Asghar Davood, Design and synthesis of 3-benzyl derivatives of ciprofloxacin as new cytotoxic agents, The 13th Iranian pharmaceutical Sciiences Congress (IPSC 2012), Isfahan, Iran, 2012;7(5).

  1. Asghar Davood, Elahe Qudjani, Design and synthesis of novel curcumin analogues as potential anticancer agents, 9th international brest cancer (2013).

  1. Zeynab Khansepid, Asghar Davood, Design and synthesis of new derivatives of N-hydroxyurea, 6th International congress of laboratory and clinic, Tehran, Iran (2014).

  1. Adeleh Farrahi, Asghar Davood, Alireza Forumadi, Design and synthesis of new 3-benzyl quinolones derived from ofloxacin with potential cytotoxic effect, 1th international pediatric oncology congress (2014).

  1. Adeleh Farrahi, Asghar Davood, Alireza Foroumadi, Design and synthesis of new 3-benzyl quinolones derived from ofloxacin with potential Topoisomerase II inhibitory effect, 15th Iranian and international congress of microbiology, Tehran, Iran (2014).

  1. Maryam Nikravesh, Asghar Davood, Design and synthesis of new 2,5-disubstituted phthalimide as potential anticonvulsant agents, 11th International congress on epilepsy, Iran, Tehran, (2015).

  1. Yasaman Rasouli, Asghar Davood, Docking studies of a series of 1,4-dihydropyridine dicarboxamide as new atni-tubercular agents, The 23rd Iranian congress on infectious diseases and tropical medicine, Tehran, Iran, P110 (2015).

  1. Yasaman Rasouli, Asghar Davood, Design of new derivatives of 1,4-dihydropyridine dicarboxamide as potential anti-tubercular agents, 5th International congress of newest research achievment in medical sciences, Tehran, Iran, (2014).

  1. Maryam sadat Yadavar Nikravesh, Asghar Davood, Synthesis of new N-biphenyl phthalimide as potential anticonvulsant agent, 3rd Neuroscience congress, Tehran, Iran (2014).

  1. Maryam sadat Yadavar Nikravesh, Asghar Davood, Design and synthesis of new 2,5-disubstituted phthalimide as potential anticonvulsant agents, 5th International congress of newest research achiievement in medical sciences, Tehran, Iran, (2014).

 

Doing research :

  1. Design and synthesis of phthalimide and homophthalimide derivatives as anticonvulsant and COX-inhibitor.
  2. Design and synthesis of curcumin derivatives as a new cytostatic agents.
  3. Design and synthesis of dihydropyridines as a  antitubercular agents.
  4. Design and synthesis of 3-benzylfluroquinolones as a new cytotoxic agents
  5. Design and synthesis of hydrazine derivatives as hypoglycemic agent (glucose-6-phosphatase inhibitor)
  6.  Design and synthesis of semicarbazides and thiosemicarbazides as a antitubercular and cytotoxic agents.
  7.  Design and synthesis of azoles as a antifungal agents.
  8. Computer aided drug design: Docking, QSAR  and protein homology modeling.
  9. Extraction ,purification and structure identification of natural product.

Interests and future programs:

  1. Design and synthesis of new antialzheimer agents.
  2. Natural product as LEAD compound; docking, virtual screening and  synthesis of new derivatives to finding a new drugs
  3. Polymer synthesis
  4. Protein Structure Modeling